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What is Percocet? Percocet contains a combination form of Oxycodone and acetaminophen. It helps relieve moderate to severe pain. Oxycodone is an opioid (sometimes called a narcotic) pain medication. Acetaminophen is a less potent pain reliever that increases the Oxycodone effects. Due to addiction, abuse, and misuse risks, even at prescribed doses, Percocet is only for use when treatment with the non-opioid pain-relieving drugs is intolerable or unable to provide adequate pain relief. How to take Percocet? Take Percocet precisely ... more